Bioclinic Naturals B12 Methylcobalamin 5000 mcg 60 loz
Description
B12 Methylcobalamin 5000 mcg 60 loz
Description:
Vitamin B12 is the cofactor in enzymatic reactions with diverse physiological functions. It is required for the conversion of methylmalonyl CoA to succinyl CoA, as well as the conversion of homocysteine to methionine by methionine synthase, which is then converted into S-adenosylmethionine. A B12 deficiency causes impairments in both of these pathways, disrupting neurological function, including poor formation of myelin nerve sheaths, production of toxic levels of homocysteine, and inefficient energy production in all cells.
Because of its relationship to myelin production and neurological function, high dose B12 has been used in a variety of neurodegenerative diseases, including Parkinson’s disease, amyotrophic lateral sclerosis, and multiple sclerosis. Nutritional Facts:
Serving Size: 1 Lozenge
Servings per Container: 60
Amount per Serving:
Vitamin B-12 (as methylcobalamin) 5,000 mcg Ingredients:
Inactive Ingredients: Lactose (from milk), cellulose, croscarmellose sodium, magnesium stearate (vegetable grade). Directions:
1 lozenge per day or as directed by a health care professional. Chew or hold in mouth until dissolved. Contains no artificial preservatives, colors or sweeteners; no corn, gluten, soy, starch, wheat or yeast. Contraindication:
B12 is contraindicated in patients with hereditary optic neuropathy, and may be cautioned against at high doses in oncology patients because of its role in DNA synthesis. Supplemental folic acid may mask a B12 deficiency, which should be ruled out, and folic acid and increased potassium intake is recommended with B12 therapy. B12 is considered safe in pregnant and lactating women, and may be indicated in children with a low dietary intake.
Description:
Vitamin B12 is the cofactor in enzymatic reactions with diverse physiological functions. It is required for the conversion of methylmalonyl CoA to succinyl CoA, as well as the conversion of homocysteine to methionine by methionine synthase, which is then converted into S-adenosylmethionine. A B12 deficiency causes impairments in both of these pathways, disrupting neurological function, including poor formation of myelin nerve sheaths, production of toxic levels of homocysteine, and inefficient energy production in all cells.
Because of its relationship to myelin production and neurological function, high dose B12 has been used in a variety of neurodegenerative diseases, including Parkinson’s disease, amyotrophic lateral sclerosis, and multiple sclerosis. Nutritional Facts:
Serving Size: 1 Lozenge
Servings per Container: 60
Amount per Serving:
Vitamin B-12 (as methylcobalamin) 5,000 mcg Ingredients:
Inactive Ingredients: Lactose (from milk), cellulose, croscarmellose sodium, magnesium stearate (vegetable grade). Directions:
1 lozenge per day or as directed by a health care professional. Chew or hold in mouth until dissolved. Contains no artificial preservatives, colors or sweeteners; no corn, gluten, soy, starch, wheat or yeast. Contraindication:
B12 is contraindicated in patients with hereditary optic neuropathy, and may be cautioned against at high doses in oncology patients because of its role in DNA synthesis. Supplemental folic acid may mask a B12 deficiency, which should be ruled out, and folic acid and increased potassium intake is recommended with B12 therapy. B12 is considered safe in pregnant and lactating women, and may be indicated in children with a low dietary intake.
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